Hundreds of years into the future, Earth has colonized Mars but Mars is now independent, and the two planets are in a constant state of distrust and unease. Caught between these two are the people of the asteroid belt and outer planets. James Holden, the executive officer of a freighter witnesses his ship, being destroyed by what appears to be a Martian warship. This heightens the tensions between Earth and Mars and sets Holden and his remaining crew on a quest across the solar system to find the truth behind the incident. Meanwhile, on Ceres in the Asteroid Belt, a police detective is searching for the daughter of one of the wealthiest men in the System. These are all parts of a conspiracy that will threaten all life in the Solar System.